中国科学技术大学生命科学与医学部讲席教授、博士生导师,常务副书记、副部长;“长江学者奖励计划” 特岗教授;中国免疫学会常务理事,中国免疫学会肿瘤免疫与生物治疗专业委员会副主任委员,中国免疫学会生殖免疫专业委员会副主任委员,安徽省免疫学会理事长。主要从事天然免疫研究,为首承担国家重点研发计划重点专项项目1项(首席),国家自然科学基金重点项目5项,国家863课题2项,国家973课题2项,国家新药创制重大专项1项,中国科学院先导科技专项1项。已发表SCI收录论文226 篇,以通讯作者在Nature Immunology,Immunity,Cell Metabolism,Science Translational Medicine,Nat Commun,PNAS, Blood, Hepatology,Gastroenterology,Cancer Res, PLoS Pathog等重要学术刊物发表论文70余篇,2008年获国家自然科学二等奖1项,2007年和2010年获中华医学科技一等奖各1项,2016年获安徽省自然科学一等奖1项,2020年获全国抗击新冠肺炎疫情先进个人,2021年获国家卫健委“吴杨奖”,2021年获教育部“全国高校黄大年式教师团队”负责人。
近期代表性论文:
Xiaohu Zheng, Zhuanghao Hou, Yeben Qian, Yongwei Zhang, Quanwei Cui, Xuben Wang, Yiqing Shen, Zhenbang Liu, Yonggang Zhou, Binqing Fu, Rui Sun, Zhigang Tian, Guangming Huang and Haiming Wei*. Tumors evade immune cytotoxicity by altering the surface topology of NK cells. Nature Immunology. 2023 May;24(5):802-813
Wang D, Sun Z, Zhu X, Zheng X, Zhou Y, Lu Y, Yan P, Wang H, Liu H, Jin J, Zhu H, Sun R, Wang Y, Fu B, Tian Z, Wei H*. GARP-mediated active TGF-β1 induces bone marrow NK cell dysfunction in AML patients with early relapse post-allo-HSCT. Blood. 2022 Aug 18; blood.2022015474
Wei H* and Fu B*. Make killers sweeter: targeting metabolic checkpoints of NK cells. Nature Immunology. 2020 Sep;21(9):970-971
Zhou Y, Fu B*, Xu X, Zhang J, Tong X, Wang Y, Dong Z, Zhang X, Shen N, Zhai Y, Kong X, Sun R, Tian Z*, Wei H*. PBX1 expression in uterine natural killer cells drives fetal growth. Science Translational Medicine. 2020 Apr 1; 12(537):eaax1798
Xu X*, Han M, Li T, Sun W, Wang D, Fu B, Zhou Y, Zheng X, Yang Y, Li X, Zhang X, Pan A, Wei H*. Effective treatment of severe COVID-19 patients with tocilizumab. PNAS. 2020 May 19; 117(20):10970-10975.
Zhou Y, Fu B, Zheng X, Wang D, Zhao C, Qi Y, Sun R, Tian Z, Xu X*, Wei H*. Pathogenic T-cells and inflammatory monocytes incite inflammatory storms in severe COVID-19 patients. National Science Review, 2020 Mar 13; 7(6) : 998-1002
Zheng X, Qian Y, Fu B, Jiao D, Jiang Y, Chen P, Shen Y, Zhang H, Sun R, Tian Z*, Wei H*. Mitochondrial fragmentation limits NK cell-based tumor immunosurveillance. Nature Immunology. 2019 Dec; 20(12):1656-1667
Cong J, Wang X, Zheng X, Wang D , Fu B, Sun R, Tian Z*, Wei H*. Dysfunction of Natural Killer Cells by FBP1-induced Inhibition of Glycolysis during Lung Cancer Progression. Cell Metabolism. 2018 Aug 7;28(2):243-255.e5
Fu B, Zhou Y, Ni X, Tong X, Xu X, Dong Z, Sun R, Tian Z*, Wei H*. Natural killer cells promote fetal development through the secretion of growth-promoting factors. Immunity. 2017 Dec 19;47(6):1100-1113
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日期 | 时间 | 会场 | Session | 角色 | 讲题 |
---|---|---|---|---|---|
2024-10-18 | 16:05-16:30 | 分会场三(二层 百宴厅4) |
免疫与感染 |
讲者 | 微生物感染发生发展的免疫学基础 |